Is There Decreasing Prevalence of Helicobacter Pylori Infection in Patients with Dyspepsia?

Background: Word-wide there is decreasing prevalence of Helicobacter pylori (H. Pylori) infection. As we are lacking in consistent data regarding H. Pylori infection our polpulation, aimed to find out H.pylori patients with dyspepsia Nort-East part Bangladesh. 
 Material and methods: Clinical variables, stool antigen test result endoscopic findings consecutive were recorded a semi-structured questionnaire. Statistical analysis was done SPSS programme 17.0(). Significance level set at 0.05 or less.
 Results: A toal 790 (male 549, female 241) included the study higher mean age among (41.46 VS. 39.19, p.008) than male patients. Three most common dyspetic symptoms abdominel pain (n=365, 46.2%), bloating (n=280, 35.4%) vomiting (n=163, 20.6%). total 217(39.5%) 87(36.0%) positive for (n=308, 38.5%) pylori. No significant association found between presence individual dyspeptic symptom, number (OR 1.385, p .103), .998, .668), sex 1.157, .362), rural/urban residence 1.126, .503) socioeconomic condition .965, .09). Around 81% (293/360) subjects had upper GI lesion (Gastritis/gastric ulcer, duoudenitis/duodenalulcer, oesophagitis/ulcer) endoscopy antigent positivity paietnts duodenal gastric lesions (37% 36.6%) comparable.
 Conclusion: rate favour declining comparison previous sudies. Majority upperGI endoscopy. sigficant differece noted pyori anong PPI takers non-takers.
 JCMCTA 2022 ; 33 (1) : 97-102